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Research use only.
KPV is a synthetic tripeptide (lysine-proline-valine) corresponding to the C-terminal fragment of α-melanocyte-stimulating hormone (α-MSH), characterized in published research as an anti-inflammatory peptide. It is used as a laboratory tool for investigating inflammatory signaling and immune-cell response in cellular and in vitro model systems.
Its activity has been examined in preclinical research as a reference compound for probing NF-κB pathway modulation, pro-inflammatory cytokine regulation, and melanocortin-related signaling mechanisms.
KPV has been referenced in peer-reviewed publications examining anti-inflammatory peptide pharmacology and mucosal inflammation. This product is intended for research use only.
Inflammatory Signaling Research Investigated in preclinical models for its effects on NF-κB pathway activation and pro-inflammatory signaling cascades.
Mucosal & Intestinal Research Examined in animal models for observations related to intestinal epithelial inflammation and mucosal immune response.
Receptor & Transport Pharmacology Research Studied in laboratory research for interactions with melanocortin receptor binding and PepT1-mediated cellular uptake.
Cytokine & Immune Response Research Evaluated in preclinical tissue models for observations related to pro-inflammatory cytokine regulation and immune-cell activity.
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months. Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.
Reconstitute slowly by adding solvent to the side of the vial and allowing it to dissolve without agitation. Do not shake. Store away from direct light. All products are shipped with dry ice or cold packs to maintain cold-chain integrity.
All KPV batches are independently tested by a third-party laboratory for purity and identity verification via HPLC with UV detection coupled with Mass Spectrometry.
| Test | Method | Specification | Result |
|---|---|---|---|
| Peptide Identity | Mass Spectrometry | Confirmed | Identity Confirmed |
| HPLC Purity | Reverse-Phase HPLC | ≥99% | 99.2% — Pass |
| Endotoxin (LAL) | LAL Assay | <1.0 EU/mg | <0.8 EU/mg — Pass |
| Heavy Metals | ICP-MS | Below USP limits | All Below Threshold |
| Appearance | Visual | White lyophilised powder | Pass |
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