Research Use Only | Not for Human Consumption

PT-141

A synthetic cyclic heptapeptide analog of alpha-MSH, supplied in lyophilized form. PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide derived from alpha-melanocyte-stimulating hormone. In preclinical research, it has been examined as an agonist of melanocortin receptors, with a focus on MC4R binding and downstream intracellular signaling in neuronal cell models.

CAS#

Formula

Molar Mass

189691-06-3
C₅₀H₆₈N₁₄O₁₀
1025.2 g/mol

Select Size

Price per unit

$54.00

Research use only.

What is PT-141?

PT-141, also called Bremelanotide, originated from Melanotan 2 research at the University of Arizona. Scientists there were characterizing melanocortin receptor analogs and observed MC4R-mediated signaling activity distinct from the melanogenesis pathways that were the original focus of investigation.

Researchers subsequently modified the Melanotan 2 structure to produce a cyclic heptapeptide with altered receptor selectivity. The resulting compound, PT-141, has since appeared in peer-reviewed preclinical and clinical publications examining melanocortin receptor binding and central nervous system signaling.

Bremelanotide has been the subject of published clinical pharmacology investigations. The research-grade form is used in melanocortin receptor signaling studies. This product is intended for research use only.

What is PT-141 studied for?

Tissue Regeneration Research
Investigated in preclinical models for its effects on muscle, tendon, and ligament tissue repair mechanisms.

Wound Healing Research
Examined in animal wound models for observations related to tissue closure and ulcer repair pathways.

Anti-inflammatory Research
Studied in laboratory research for interactions with inflammation-related signaling pathways across various tissue types.

Gastrointestinal Research
Evaluated in preclinical GI tissue models for observations related to gastric and intestinal mucosal integrity.

How should PT-141 be stored?

All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months. Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.

Lyophilised (Unopened)
−20°C for up to 24 months
Reconstitution Solvent
Bacteriostatic water recommended
Reconstituted Solution
2–8°C for up to 28 days
Avoid
Repeated freeze-thaw cycles

Handling Notes

Reconstitute slowly by adding solvent to the side of the vial and allowing it to dissolve without agitation. Do not shake. Store away from direct light. All products are shipped with dry ice or cold packs to maintain cold-chain integrity.

Certificate of Analysis

All PT-141 batches are independently tested by a third-party laboratory for purity and identity verification via HPLC with UV detection coupled with Mass Spectrometry.

Test Method Specification Result
Peptide Identity Mass Spectrometry Confirmed Identity Confirmed
HPLC Purity Reverse-Phase HPLC ≥99% 99.2% — Pass
Endotoxin (LAL) LAL Assay <1.0 EU/mg <0.8 EU/mg — Pass
Heavy Metals ICP-MS Below USP limits All Below Threshold
Appearance Visual White lyophilised powder Pass
Independent Lab Verified · Full PDF COA Available on Request

Related Research Compounds

PT-141 is available for laboratory research purposes only. © 2026 Pharma Peptides LLC | Product Catalog | Research Use Only